Search results for "Peptide sequences"

showing 2 items of 2 documents

Enzyme-Mediated Controlled Release Systems by Anchoring Peptide Sequences on Mesoporous Silica Supports

2011

[EN] Gated community: Peptides anchored to the surface of silica mesoporous supports by a valid procedure act as gatekeepers. In this way, "zero release" supports that selectively deliver the cargo in the presence of a suitable peptidase are obtained (see picture, red spheres: cargo, colored chains: peptides). © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

INGENIERIA DE LA CONSTRUCCIONPeptide sequencesStereochemistryPeptide hydrolaseMolecular Sequence DataAnchoringPeptideCatalysisRutheniumArticleAmino acid sequenceNanoparticleQUIMICA ORGANICACoordination ComplexesControlled release systemsSilicon dioxideControlled releaseOrganic chemistryMolecular geneticsValenciachemistry.chemical_classificationbiologyQUIMICA INORGANICAMesoporous supportSilicaGeneral ChemistryGeneral MedicineMesoporous silicaMolecular gatesbiology.organism_classificationControlled releaseMesoporous materialsChemistryKineticsEnzymeMetabolismchemistryMesoporous SilicaPeptide HydrolasesPeptideNanoparticlescontrolled releasePeptidesPorosityCoordination compoundmolecular gatesPeptide HydrolasesAngewandte Chemie
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Poly-Xaa Sequences in Proteins - Biological Role and Interactions with Metal Ions: Chemical and Medical Aspects

2016

Background: The understanding of the bioinorganic and coordination chemistry of metalloproteins containing unusual poly-Xaa sequences, in which a single amino acid is repeated consecutively, is crucial for describing their metal binding-structure-function relationship, and therefore also crucial for understanding their medicinal potential. To the best of our knowledge, this is the first systematic review on metal complexes with polyXaa sequences. Methods: We performed a thorough search of high quality peer reviewed literature on poly-Xaa type of sequences in proteins, focusing on their biological importance and on their interactions with metal ions. Results: 228 papers were included in the…

Metal ions in aqueous solutionComputational biology010402 general chemistry01 natural sciencesBiochemistryCoordination complexTurn (biochemistry)metal chaperonesCoordination ComplexesDrug DiscoveryMetalloproteinHumansAmino Acid SequenceSingle amino acidAmino AcidsBinding siteantimicrobial therapeuticsIonsPharmacologychemistry.chemical_classification010405 organic chemistryMetal bindingOrganic Chemistrymetal ionsProteinsBioinorganic chemistry0104 chemical scienceschemistryChemical physicsMetal-protein complexespoly-Xaa peptide sequencesMolecular MedicineCurrent Medicinal Chemistry
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